ABSTRACT
Hydatidiform mole is an abnormal gestation characterized by trophoblastic hyperplasia and overgrowth of placental villi. H. mole is classified as complete (CHM) and partial (PHM). The diagnosis is based on histopathology and genetic origin. In our set up, we used only histopathological diagnostic criteria. The incidence of molar pregnancy varies in different parts of the world. Objective of the present study was to determine the frequency, clinical presentation and morphological features of H. mole and compare them with those of other studies. Objectives: The aim of this populationbased retrospective study was to evaluate the trend in the incidence of molar pregnancy. The reported incidence of GTD in India is in consistent therefore we planned to do an analysis of the GTD at our institute which is a referral tertiary center of Punjab. Methods: Records of patients of GTD admitted from Dec 2016 to March 2018 were analyzed and incidence was calculated. The diagnosis of hydatidiform mole was based on the post-operative morphological and/or pathological findings. A total of 150 cases of retained products of conception received in the department of pathology were analysed. Results: Out of total 16 cases of molar pregnancy 5 were diagnosed as complete mole and 11 were diagnosed as partial mole. Out of 5 cases of complete mole, one case was of recurrent molar pregnancy. Conclusion: There is a need to look further about the association of age with molar pregnancies in future studies.
ABSTRACT
Background: The tubo-ovarian lesions manifest a wide spectrum of clinical, morphological, and histological features. Aims and objectives- To classify the lesions of tubes and ovaries and to correlate the various clinical and histopathological findings with age, chief complaints, and microscopic appearances of lesions. To correlate them radiologically and histopathologically. Methods: The present prospective study was based on the clinico-pathological correlation of various tubo-ovarian lesions in 75 cases over a period of 2 years. The histopathological reports were used to classify the tubo-ovarian lesions and correlate /substantiate the clinical and radiological findings. Results: Out of 75 cases, 51 (68%) ovarian, 18 (24%) tubal, and 6 (8%) cases showed simultaneous involvement of both tube and ovary. Amongst 18 tubal lesions,16 were of ectopic gestation (6 were ruptured) and the rest 2 of salpingitis. Amongst the ovarian lesions,41 cases were of ovarian neoplasms which were categorized as benign and malignant. Serous cystadenoma was the most common benign tumor and serous cystadenocarcinoma was the most malignant tumor. Conclusion: Clinical, radiological and histopathological diagnosis were compared and analysed statistically and the correlation was highly significant. An accurate clinical and radiological examination along with the histopathological examination aids in improving the diagnostic accuracy.